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Get a refill for your existing Glimepiride prescription online

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One-time visit with a physician for diagnosis, treatment, Rx, labs, referrals, and doctor’s notes.
Copay or $129 without insurance.
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You can request a refund after your visit if we are unable to provide care.
Having a visit does not guarantee a medication will be ordered or refilled. It is clinicians’ professional decision. It is prohibited by law to prescribe or refill controlled substances via virtual visits. Your provider may recommend follow-up care, including additional services that may not be included in visit price.

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Glimepiride (Generic Amaryl)

What is Glimepiride?

Glimepiride is a medication used to treat type 2 diabetes. It causes the pancreas to secrete insulin, which lowers blood sugar. It is used together with diet and exercise, and might also be used together with other medication. 

Glimepiride is only effective for someone whose pancreas naturally produces insulin. It’s not used to treat type 1 diabetes. Glimepiride is taken as an oral medicine, as a tablet that is usually taken once per day.

How does Glimepiride work?

Glimepiride works by increasing the amount of insulin produced by the pancreas. It is part of a group of compounds called sulfonylureas, which stimulate the cells in the pancreas that produce insulin. 

This means that the pancreas needs to produce at least some insulin on its own for Glimepiride to work. More insulin in the body helps to control high blood sugar, which in turn can help to prevent heart attack, stroke, and other health complications.

What is Glimepiride used for?

Glimepiride is used to treat type 2 diabetes. This type of diabetes is the most common and is usually diagnosed in adults, whereas the rarer type 1 diabetes is more often diagnosed in children. Type 2 diabetes is caused by both genes and lifestyle. 

Glimepiride is not often used for people newly diagnosed with type 2 diabetes. Instead, metformin, a medicine that reduces insulin resistance is often prescribed first. However, Glimepiride may be diagnosed as an alternative medicine on its own or together with other medicines.

What are the side effects of Glimepiride?

Glimepiride has a number of potential side effects. Some side effects are more common than others, but it’s still important to be aware of more severe side effects that could occur.

Common side effects

  • Nausea
  • Indigestion
  • Diarrhea

Glimepiride can sometimes cause low blood sugar. It’s important to make sure you eat enough if you’re taking it. Keeping some snacks handy can help to prevent this.

Severe side effects

  • Liver problems – yellowing of the eyes or skin can be an indication of this
  • Blood disorders – symptoms include unusual bleeding or bruising
  • Increased risk of heart problems

How to take Glimepiride?

Glimepiride is taken as a tablet. It is usually taken once per day with the first meal of the day. Taking it at around the same time each day can help to make it easier to remember. If you are prescribed glimepiride, your doctor can advise you on what to do if you miss a dose. Usually, the advice will be to take it as soon as you remember, but this may depend on how close you are to the next dose. Make sure that you take Glimepiride as directed by your doctor.

Glimepiride is often prescribed in a low dose at first, which may be increased if it becomes less effective. Your doctor will monitor how the medicine is working for you. It is also important to work on the lifestyle factors that can help you control type 2 diabetes, including a healthy diet and plenty of exercise.

Frequently Asked Questions About Glimepiride

Is Glimepiride Safe?

Glimepiride is considered generally safe when taken as prescribed. If you experience any side effects, it’s important to speak to your doctor. You should also tell your doctor if you have any pre-existing conditions or allergies that may be affected by taking Glimepiride.

But just like any other medication, Glimepiride does have risks associated with it and it may not be suitable for everyone.

What to Avoid While Taking Glimepiride?

If you are prescribed Glimepiride, you should avoid the following:

  • Alcohol – Drinking alcohol while taking Glimepiride can increase the risk of low blood sugar (hypoglycemia).
  • Long exposure to sunlight – Glimepride can make the skin more sensitive to light and you might get a sunburn more easily.
  • Excessive physical activity – Glimepiride may cause low blood sugar, which can be worsened by excessive physical activity.
  • Skipping meals – Glimepiride only works when your pancreas produces some insulin, so skipping meals can lead to low blood sugar.

The list above is not exhaustive and there are many other things to consider when taking Glimepiride, so it is important to speak to your doctor if you have any questions.

Glimepiride can also interact with certain prescription and OTC medications and supplements, so speak to your doctor or pharmacist about these before taking them.

How Long Does It Take for Glimepiride to Work?

Glimepiride starts working rather quickly after taking it. It usually takes around 2 to 3 hours for it to reduce your blood sugar levels.

What Is the Typical Dosage for Glimepiride?

The typical starting dosage for Glimepride is 1 to 2 mg taken once a day taken with your first meal of the day.

Your doctor may increase the dosage to a maximum of 8 mg per day if needed. However, it is important to only take the dosage prescribed by your doctor as taking too much Glimepiride can be dangerous.

Is Glimepiride Stronger Than Metformin?

While both Glimepiride and Metformin are used to treat type 2 Diabetes, their effects are different and they have distinct mechanisms of action.

  • Glimepiride belongs to the sulfonylurea class of drugs. It works primarily by stimulating the pancreas to produce more insulin.
  • Metformin is a biguanide. It primarily reduces glucose production in the liver and improves insulin sensitivity, leading to better glucose uptake and utilization by the cells.

While both of these drugs are efficient, it ultimately depends on your individual situation which one works best for you. It is important to consult with your doctor and follow their advice as they will be able to provide the right dosage and drug combination that works best for you.

Can You Get Glimepiride Over-The-Counter (OTC)?

No, you can’t get Glimepiride over-the-counter. Currently in the US Glimepiride is only available with a prescription. So you will need to get a valid prescription from a licensed medical professional.

Can You Get a Prescription for Glimepiride From DrHouse?

Yes, you can indeed receive an online prescription for Glimepiride through DrHouse, if our licensed medical professionals determine it to be an appropriate course of treatment for you. This involves a comprehensive evaluation of your medical history and current health condition during a virtual consultation.

For more detailed information about Glimepiride, you can refer to the following sources:

Content on the DrHouse website is written by our medical content team and reviewed by qualified MDs, PhDs, NPs, and PharmDs. We follow strict content creation guidelines to ensure accurate medical information. However, this content is for informational purposes only and not a substitute for professional medical advice, diagnosis, or treatment. For more information read our medical disclaimer.

Always consult with your physician or other qualified health providers about medical concerns. Never disregard professional medical advice or delay seeking it based on what you read on this website.

If you are experiencing high fever (>103F/39.4C), shortness of breath, difficulty breathing, chest pain, heart palpitations, abnormal bruising, abnormal bleeding, extreme fatigue, dizziness, new weakness or paralysis, difficulty with speech, confusion, extreme pain in any body part, or inability to remain hydrated or keep down fluids or feel you may have any other life-threatening condition, please go to the emergency department or call 911 immediately.

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Frequently asked questions

  • Yes, you can get a new prescription or refill an existing one online through DrHouse. You just need to start a consultation with one of our licensed providers and they will be able to assess your needs and provide you with a prescription if necessary.

    Please note that the final decision always rests with the doctor based on their professional judgment and your health needs.

  • There are certain medications that cannot be prescribed online by DrHouse physicians due to safety reasons. These include controlled substances, such as opioids and other narcotics, as well as drugs with a high potential for abuse or dependence. DrHouse physicians also don’t prescribe Gabapentin, medical marijuana, muscle relaxants, and HRT medications.

  • With DrHouse getting a new prescription or a refill for your current Rx is a straightforward and quick process. All you need to do is follow a few easy steps:

    • Download the DrHouse telehealth app on your mobile device.
    • Create an account by providing basic information and medical history.
    • Start an on-demand virtual video consultation with one of our licensed physicians.
    • Discuss your medical needs and concerns with one of our physicians.
    • A doctor will review your medical history, symptoms, and current medications (if any) to determine if an online prescription is appropriate for you.
    • If a physician approves, they will electronically send a new prescription or refill request to the pharmacy of your choice.
    • Pick up your medication from the pharmacy.

    DrHouse makes it easy for you to get an online prescription from the comfort of your own home. No more waiting in line at the doctor’s office or pharmacy, and no need to take time off work to see a doctor. Our telehealth platform allows you to access quality medical care from anywhere with an internet connection.

    For more information about how our telehealth platform works visit our “How DrHouse Works” page.

  • During your virtual consultation with a DrHouse physician, you will have the opportunity to discuss your medical needs and concerns.

    The consultation will consist of a video call where a physician will assess your medical history and ask you questions about your symptoms and any other relevant information. This is to ensure that a physician has all the necessary information to make an informed decision about your prescription.

    You can also ask any questions or clarify any doubts you may have about your condition or medication. Our physicians are happy to address any concerns you may have.

    Once a physician has assessed your needs, they will determine if and what type of prescription is appropriate for you. If a new prescription or refill is approved, a doctor will send it electronically to your chosen pharmacy.

  • With our on-demand telehealth service, you have the opportunity to see the first available doctor in as little as 10 to 15 minutes. However, the exact consult time will depend on the complexity of your case and the thoroughness required by the healthcare provider to make an informed decision.

  • Absolutely, it is safe to get an online prescription from DrHouse. We are committed to ensuring the highest standards of patient safety and privacy.

    All our providers are highly qualified US-based physicians and often affiliated with major hospitals. They are board-certified and from the top U.S. medical schools with an average of 20 years of experience.

    We strictly adhere to HIPAA regulations, ensuring your personal and medical information is kept secure and confidential. Also, we comply with all applicable state and federal laws related to telehealth and the prescribing of medications.

    Therefore, you can rest assured knowing that your safety and privacy are our top priorities when you use DrHouse’s services.

  • DrHouse strives to provide accessible and affordable telehealth services. DrHouse urgent care, primary care, and specialist visits are $129 or your copay. This includes everything from your initial consultation through to the prescription of your medication.

    The cost of a doctor’s visit may be covered fully by your insurance. A typical copay is around $25. We recommend checking with your insurance provider to understand the extent of your coverage for telehealth services.

    To learn more about how much DrHouse costs, visit our pricing page

  • Yes, DrHouse accepts most major insurances, including Blue Cross Blue Shield, Aetna, and Medicare. The extent of coverage may vary depending on your individual plan.

  • Our physicians are able to prescribe up to a 90-day prescription without labs for any previously prescribed medication if it’s medically appropriate and is not classified as a controlled substance.

    DrHouse physicians also don’t prescribe Gabapentin, medical marijuana, muscle relaxants, and HRT medications.

    DrHouse physicians use their medical judgment to determine whether to prescribe and the duration.

    In certain cases, the prescription may be limited to 30 days or less. There also may be a 12-month cap for some prescriptions without labs. For medications requiring annual monitoring (such as blood work or imaging), the maximum prescription limit is 90 days within a year without labs.

    DrHouse physicians can refer patients to labs for longer prescription periods or refills.