Get a Methylprednisolone
Prescription Online

Get a new Methylprednisolone prescription or refill your medication online.

Get a Prescription

Available in 50 states. No insurance needed.

virtual visits
24/7 care
as needed
Online prescription mobile presentation mockup
24/7 Personal Care
Consult with a clinician in 15 minutes,
refill an Rx or chat with our care assistants.
Affordable & Convenient
See your cost upfront and get treatment for hundreds of different conditions.
No Insurance Needed
No insurance? No worries! Our board-certified clinicians are at your reach.
How to get a Methylprednisolone prescription online?

Download the DrHouse app. Set up your free account in a minute.


Start a visit with an online doctor. Wait time is less than 15 minutes.


Get an Rx from your preferred pharmacy. Pick up an Rx nearby or get it delivered to you.

Download our app

How much does a visit to get a Methylprednisolone prescription cost?

Physician Visit
One-time visit with a physician for diagnosis, treatment, Rx, labs, referrals, and doctor’s notes.
Copay or $129 without insurance.
24/7 virtual visits
See the first available physician, or schedule a visit with a physician you like.
Live customer support
Chat with our customer support whenever necessary. They are here for you 24/7.
Get a real doctor’s note
Get a doctor’s excuse and/or clearance for your school or work if needed.
100% treatment guarantee
You can request a refund after your visit if we are unable to provide care.
Having a visit does not guarantee a medication will be ordered or refilled. It is clinicians’ professional decision. It is prohibited by law to prescribe or refill controlled substances via virtual visits. Your provider may recommend follow-up care, including additional services that may not be included in visit price.

See why people turn to DrHouse...


Methylprednisolone (Generic Medrol)

What Is Methylprednisolone?

Methylprednisolone is classified as a corticosteroid drug. It is prescribed as an anti-inflammatory drug, treating inflammation caused by various factors or conditions throughout the body. Many patients are prescribed this drug if they suffer from arthritis or certain allergies. 

This medication is often prescribed as an oral tablet and will usually be sold under the brand name Medrol. 

How Does Methylprednisolone Work?

As mentioned previously, Methylprednisolone is a corticosteroid with anti-inflammatory properties. It is also considered an immunosuppressant due to how it works. 

A corticosteroid like Methylprednisolone will replicate the glucocorticoid hormones secreted by your adrenal glands. Certain conditions can inhibit the body’s ability to naturally produce this particular hormone. As a result, the immune system has a negative response and believes it needs to fight to protect the body from danger. This immune response typically leads to increased inflammation. 

Methylprednisolone gives the body synthetic glucocorticoid hormones, which help to prevent this negative immune response. Instead, inflammation is reduced and the immune system is calmed down. Therefore, it can be used to treat a wide range of inflammatory and immune system conditions. 

What Is Methylprednisolone Used For?

Doctors are likely to prescribe Methylprednisolone for any of the following conditions: 

  • Arthritis
  • Asthma
  • Certain allergic reactions
  • Blood disorders
  • Crohn’s disease
  • Ulcerative colitis
  • Multiple sclerosis

All of these conditions either cause inflammation or occur as a result of an overactive immune system. It is also possible to see Methylprednisolone used to treat various skin conditions that are triggered by inflammation. 

In rare instances, this drug has been used to treat some forms of cancer too. However, this is typically for palliative care as a pain reliever, rather than to help cure the cancer itself. 

What Are the Side Effects of Methylprednisolone?

Methylprednisolone may cause a multitude of side effects due to its effect on the immune system and the human body as a whole. 

The majority of these side effects are mild and will not be a cause for alarm. These include: 

  • Mild stomach pain
  • Mild nausea
  • Headaches
  • Dizziness 
  • Difficulty sleeping
  • Increased anxiety
  • Changes to menstruation
  • Acne/pimple growth
  • A sense of restlessness

You might experience some of these symptoms when you first start taking Methylprednisolone. In most cases, they will fade away or become easier to manage as your body adjusts to the medication. If the side effects do not improve – or get severely worse – you should tell your doctor and temporarily stop taking the medication until further notice. 

Some side effects of Methylprednisolone are more severe than those listed above, such as: 

  • An aggressive skin rash
  • Swelling in the face or lower legs
  • Issues with your sight/vision
  • Excessive muscle weakness
  • Black, tarry stools
  • A cold/flu that lasts longer than usual

Notify your doctor if these severe side effects are present so they can tell you what to do next. It’s likely your body has had a bad reaction to Methylprednisolone and you may need a reduced dose or a different type of medication. 

The listed side effects are not exhaustive and you may experience something not mentioned here. You should always read through the patient information leaflet before taking Methylprednisolone and talk to your doctor about any concerns you have.

How to Take Methylprednisolone?

Take Methylprednisolone as directed by your doctor when they prescribe the medication. The exact dosage amount will be written on your prescription form. You must stick to this dosage and avoid taking more or less than suggested. 

Similarly, continue taking Methylprednisolone for as long as directed. Do not exceed the duration prescribed by your doctor as this can lead to adverse side effects. It is common for doctors to gradually decrease your prescription dose as your symptoms improve. This helps the body get used to not having Methylprednisolone in your system. Abruptly stopping this medication after taking it for a long time can also cause side effects. 

Each patient may have a different dose depending on their particular medical condition and what Methylprednisolone is being used to treat. If you accidentally forget to take a dose, do not take it along with your next dose. Missing one dose is better than taking a double dose as it could lead to problems. 

Read the information leaflet that comes with your medication as this also tells you what you can or cannot take Methylprednisolone with. Generally, it is okay to take this medication with meals. It is prescribed as an oral tablet that can be swallowed with water or milk. 

Follow your doctor’s instructions for a couple of weeks and make a note of your symptoms. If they persist and don’t show signs of improvement, talk to your doctor again. They may choose to increase your dose for improved efficacy.

Frequently Asked Questions About Methylprednisolone

Who Should Not Take Methylprednisolone?

If you’ve experienced allergic reactions to its ingredients, have systemic fungal issues, are scheduled for or have recently had live vaccinations, or deal with active infections, it’s crucial to speak with a healthcare professional before starting methylprednisolone.

Moreover, it’s essential to seek advice from a physician if you have a history of:

  • Peptic ulcers
  • Specific viral conditions, such as untreated herpes or chickenpox
  • Eye disorders like glaucoma or cataracts
  • Elevated blood pressure levels
  • Cardiac conditions or heart disease
  • Blood sugar imbalances or diabetes
  • Bone density concerns or osteoporosis
  • Mental health fluctuations, including mood swings or severe depression
  • Liver or renal challenges
  • Recent interactions with infectious diseases like measles or tuberculosis
  • Pregnancy or current breastfeeding
  • Considering its use for pediatric patients

Medications can interact in unpredictable ways and can have different effects based on individual health and history. Always ensure you’re fully informed and under the guidance of a medical professional when starting or stopping any medication.

What Is the Most Common Side Effect of Methylprednisolone?

The side effects of Methylprednisolone can vary and the most common side effects tend to be dose-dependent, which means they are more likely to occur or be more severe with higher doses.

Common side effects include:

  • Mild stomach pain
  • Mild nausea
  • Headaches
  • Dizziness 
  • Difficulty sleeping
  • Increased anxiety
  • Changes to menstruation
  • Acne/pimple growth
  • A sense of restlessness
  • Fluid retention
  • Increased blood pressure
  • Mood swings
  • Weight gain
  • Increased blood sugar levels
  • Increased risk of infections

The list above is not exhaustive and more side effects may occur. It is important to talk to your doctor if you experience any unusual or severe symptoms while taking Methylprednisolone. Your doctor might adjust the dosage or switch medication if necessary.

What to Avoid While Taking Methylprednisolone?

While taking Methylprednisolone you should avoid the following:

  • Alcohol – Alcohol can exacerbate the side effects of Methylprednisolone.
  • High-Sodium Foods – Methylprednisolone can cause your body to retain sodium, which can lead to fluid retention and increased blood pressure. Limiting your salt intake might be recommended.
  • Grapefruit and Grapefruit Juice – Grapefruit can increase the level of methylprednisolone in your bloodstream and may increase the side effects of it.
  • Caffeine – Corticosteroids like Methylprednisolone may cause you to feel jittery or anxious and drinking caffeine might exacerbate this side effect.
  • Vaccines – It may be advisable to avoid live vaccines, as your immune response can be impaired.
  • Other Medications – Some medications might interact with Methylprednisolone and should be avoided or taken with caution. Tell your doctor about all other medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements. Always inform your pharmacist if you are taking any medications before buying any new ones.

The list above is not exhaustive and there may be other activities, foods, or medications you should avoid while taking Methylprednisolone. Make sure to check with your doctor before taking any other medications or engaging in activities that may conflict with Methylprednisolone.

How Long Does It Take for Methylprednisolone to Work?

It is important to note that Methylprednisolone works differently for different people. Many factors like the patient’s age, weight, and medical condition can influence how quickly it starts working.

Generally, it takes a few days to a week or two before you start to feel the effects of Methylprednisolone.

It’s also important to note that while methylprednisolone can be very effective in reducing symptoms for various conditions, it does not cure the underlying cause of most of these conditions.

What Is the Typical Dosage for Methylprednisolone?

Methylprednisolone doses can vary from person to person and will depend on the specific condition being treated, its severity, the patient’s age, body weight, and overall health, as well as how the patient responds to the medication.

Generally, in tablet form, the typical dosage range for adults is 4 mg to 48 mg per day.

Make sure to follow your doctor’s instructions and take the medication according to their directions. Never increase or decrease the dosage without consulting your healthcare provider first. Do not stop taking methylprednisolone abruptly as this may worsen symptoms or cause other unwanted reactions.

Can You Buy Methylprednisolone Over-The-Counter (OTC)?

No, you cannot buy Methylprednisolone over-the-counter (OTC). It is only available with a prescription from a doctor or other healthcare provider.

Can You Get a Methylprednisolone Prescription Online From DrHouse?

Yes, you can get a Methylprednisolone prescription online from DrHouse if deemed appropriate by our doctors. During a video consultation with one of our licensed physicians, they will evaluate your medical history and current health condition to determine if Methylprednisolone is the right medication for you.

Can You Get a Refill for Methylprednisolone From DrHouse?

Yes, you can get a refill for Methylprednisolone from DrHouse. To refill your Methylprednisolone prescription, start a virtual visit with one of our healthcare providers. During the visit, they will assess your condition and determine if a refill is required.

If they deem it to be an appropriate treatment option for you, they will issue an online prescription which can then be filled at any pharmacy of your choice.


For more detailed information about methylprednisolone, you can refer to the following sources:

Content on the DrHouse website is written by our medical content team and reviewed by qualified MDs, PhDs, NPs, and PharmDs. We follow strict content creation guidelines to ensure accurate medical information. However, this content is for informational purposes only and not a substitute for professional medical advice, diagnosis, or treatment. For more information read our medical disclaimer.

Always consult with your physician or other qualified health providers about medical concerns. Never disregard professional medical advice or delay seeking it based on what you read on this website.

If you are experiencing high fever (>103F/39.4C), shortness of breath, difficulty breathing, chest pain, heart palpitations, abnormal bruising, abnormal bleeding, extreme fatigue, dizziness, new weakness or paralysis, difficulty with speech, confusion, extreme pain in any body part, or inability to remain hydrated or keep down fluids or feel you may have any other life-threatening condition, please go to the emergency department or call 911 immediately.

background icon medical cross left side
background icon medical cross right side

Frequently asked questions

  • Yes, you can get a new prescription or refill an existing one online through DrHouse. You just need to start a consultation with one of our licensed providers and they will be able to assess your needs and provide you with a prescription if necessary.

    Please note that the final decision always rests with the doctor based on their professional judgment and your health needs.

  • There are certain medications that cannot be prescribed online by DrHouse physicians due to safety reasons. These include controlled substances, such as opioids and other narcotics, as well as drugs with a high potential for abuse or dependence. DrHouse physicians also don’t prescribe Gabapentin, medical marijuana, muscle relaxants, and HRT medications.

  • With DrHouse getting a new prescription or a refill for your current Rx is a straightforward and quick process. All you need to do is follow a few easy steps:

    • Download the DrHouse telehealth app on your mobile device.
    • Create an account by providing basic information and medical history.
    • Start an on-demand virtual video consultation with one of our licensed physicians.
    • Discuss your medical needs and concerns with one of our physicians.
    • A doctor will review your medical history, symptoms, and current medications (if any) to determine if an online prescription is appropriate for you.
    • If a physician approves, they will electronically send a new prescription or refill request to the pharmacy of your choice.
    • Pick up your medication from the pharmacy.

    DrHouse makes it easy for you to get an online prescription from the comfort of your own home. No more waiting in line at the doctor’s office or pharmacy, and no need to take time off work to see a doctor. Our telehealth platform allows you to access quality medical care from anywhere with an internet connection.

    For more information about how our telehealth platform works visit our “How DrHouse Works” page.

  • During your virtual consultation with a DrHouse physician, you will have the opportunity to discuss your medical needs and concerns.

    The consultation will consist of a video call where a physician will assess your medical history and ask you questions about your symptoms and any other relevant information. This is to ensure that a physician has all the necessary information to make an informed decision about your prescription.

    You can also ask any questions or clarify any doubts you may have about your condition or medication. Our physicians are happy to address any concerns you may have.

    Once a physician has assessed your needs, they will determine if and what type of prescription is appropriate for you. If a new prescription or refill is approved, a doctor will send it electronically to your chosen pharmacy.

  • With our on-demand telehealth service, you have the opportunity to see the first available doctor in as little as 10 to 15 minutes. However, the exact consult time will depend on the complexity of your case and the thoroughness required by the healthcare provider to make an informed decision.

  • Absolutely, it is safe to get an online prescription from DrHouse. We are committed to ensuring the highest standards of patient safety and privacy.

    All our providers are highly qualified US-based physicians and often affiliated with major hospitals. They are board-certified and from the top U.S. medical schools with an average of 20 years of experience.

    We strictly adhere to HIPAA regulations, ensuring your personal and medical information is kept secure and confidential. Also, we comply with all applicable state and federal laws related to telehealth and the prescribing of medications.

    Therefore, you can rest assured knowing that your safety and privacy are our top priorities when you use DrHouse’s services.

  • DrHouse strives to provide accessible and affordable telehealth services. DrHouse urgent care, primary care, and specialist visits are $129 or your copay. This includes everything from your initial consultation through to the prescription of your medication.

    The cost of a doctor’s visit may be covered fully by your insurance. A typical copay is around $25. We recommend checking with your insurance provider to understand the extent of your coverage for telehealth services.

    To learn more about how much DrHouse costs, visit our pricing page

  • Yes, DrHouse accepts most major insurances, including Blue Cross Blue Shield, Aetna, and Medicare. The extent of coverage may vary depending on your individual plan.

  • Our physicians are able to prescribe up to a 90-day prescription without labs for any previously prescribed medication if it’s medically appropriate and is not classified as a controlled substance.

    DrHouse physicians also don’t prescribe Gabapentin, medical marijuana, muscle relaxants, and HRT medications.

    DrHouse physicians use their medical judgment to determine whether to prescribe and the duration.

    In certain cases, the prescription may be limited to 30 days or less. There also may be a 12-month cap for some prescriptions without labs. For medications requiring annual monitoring (such as blood work or imaging), the maximum prescription limit is 90 days within a year without labs.

    DrHouse physicians can refer patients to labs for longer prescription periods or refills.