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Having a visit does not guarantee a medication will be ordered or refilled. It is clinicians’ professional decision. It is prohibited by law to prescribe or refill controlled substances via virtual visits. Your provider may recommend follow-up care, including additional services that may not be included in visit price.

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Nystatin (Generic Nystop)

What Is Nystatin?

Nystatin is an antifungal medication that’s used to treat fungal and yeast infections in the mouth and skin.

It can be used as a liquid or an ointment, and will only work to treat infections that are fungal or yeast. This will not work on bacterial or viral infections. Your doctor or healthcare provider might prescribe this medication for other conditions, too.

How Does Nystatin Work?

As Nystatin is what’s called an antifungal medication, the purpose of the drug is to treat fungal infections. When it is used or applied, Nystatin will kill the fungus in your mouth that is causing the infection. The process can take a few days, and you should continue to use this drug for multiple days after your symptoms have cleared up to ensure that it does not come back.

What Is Nystatin Used For?

Fungal infections can develop in the mouth, as well as the lining of the stomach and your intestines.

The purpose of the medication is to counteract the infection by killing the fungus that’s causing it. 

Taking the drug will not only stop the growth of fungi in the mouth, stomach, and intestines but will also kill it to prevent it from coming back later on.

Conditions that Nystatin is commonly used to treat:

  • Oral Thrush
  • Vaginal Yeast Infections
  • Diaper Rash

The conditions mentioned above are just some of the few that Nystatin can be used to treat.

What Are the Side Effects of Nystatin?

If you have been prescribed Nystatin, you should be aware of the possible side effects that you might experience when taking the drug. Some of the more common symptoms of Nystatin are:

  • Experiencing irritation in the mouth
  • Having an upset stomach, diarrhea, or vomiting after use
  • Rashes on your skin

Taking Nystatin may also result in serious side effects, too, and if you experience any of the following you should stop taking this medication and get in touch with your healthcare provider immediately:

  • Difficulty breathing after use
  • Accelerated heart rate
  • Fever
  • Sore throat
  • Red or purple rashes on your skin.

The listed side effects are not exhaustive. If you experience any other symptoms that are out of the ordinary, it’s important to seek medical advice and assistance right away.

How to Take Nystatin?

Nystatin may come in multiple different forms with different needs of use. If you have been prescribed oral Nystatin, such as Nystatin liquid, then you should make sure to shake the bottle before use and measure out the correct amount with a syringe or appropriate piece of equipment. Once measured, put the medicine in your mouth for a minimum of 30 seconds, while swishing it around. Swallow when you can no longer keep it in your mouth.

Nystatin cream is also an available alternative, which is applied 2 to 3 times each day, and you should use it as your doctor has instructed.

You must ensure that you do not take more of this medication than you have been instructed to, as overdosing can be dangerous. If you miss a dose, take it as soon as possible, unless it is almost time for the next dose. 

You must not eat or drink anything for at least 30 minutes after taking this medication.

Frequently Asked Questions About Nystatin

What Are the Most Common Side Effects of Nystatin?

While Nystatin is generally safe to take, there are some common side effects that may occur.

The most common Nystatin side effects of oral Nystatin include:

  • Mouth irritation
  • Diarrhea
  • Upset stomach
  • Unpleasant taste in your mouth
  • Nausea

The most common Nystatin side effects of topical Nystatin include:

  • Skin irritation
  • Skin irritation
  • Temporary burning sensation

What to Avoid While Taking Nystatin?

To ensure the safety of your health, there are certain things that you should avoid while taking Nystatin.

While taking oral Nystatin avoid:

  • Alcohol – Alcohol can irritate your gastrointestinal tract and may interact with the medication.
  • Eating or Drinking after taking the medication – Eating too soon after taking Nystatin can reduce its efficacy.
  • Taking more than the prescribed amount – Overdosing can be dangerous and lead to health complications.

While using topical Nystatin avoid:

  • Other topical medication – Applying other topical medication at the same time as Nystatin can affect its efficacy.
  • Appling it on broken skin
  • Banding or covering the treated area

The things mentioned above are just some things you should avoid while taking Nystatin. Make sure to consult your healthcare provider for a comprehensive list of what you should avoid.

Can I Use Nystatin Cream on My Private Areas?

Yes, Nystatin can be used to treat yeast infections in the private area. But it’s important to get an accurate diagnosis first, as Nystatin will not work to treat bacterial infections.

If you’ve been prescribed Nystatin cream, make sure to follow your doctor’s instructions on how to apply it.

How Long Does It Take for Nystatin to Work?

The actual length of time it takes for Nystatin to work will vary from person to person and will depend on the severity and type of the infection, the form of Nystatin being used, and individual patient factors.

In general oral Nystatin, when taken for conditions like oral thrush, should show some improvement within the first few days after taking it. But it takes around a week to treat oral thrush.

For topical Nystatin it usually takes around 7 to 14 days to see a noticeable improvement.

That all said, it’s crucial to note that the exact time for Nystatin to take effect will depend on each individual and their specific condition. Make sure to follow your doctor’s advice and take the medication for as long as they have prescribed. Doing so will ensure that you get the best possible outcome from taking Nystatin.

If you don’t see any improvement after a few days it is important to contact your healthcare provider.

Can You Get Nystatin Over-The-Counter (OTC)?

No, Nystatin is a prescription-only medication and cannot be purchased over the counter. You must get a valid prescription from your healthcare provider in order to purchase this medication.


For more detailed information about nystatin, you can refer to the following sources:


The content on this page has been medically reviewed for accuracy and comprehensiveness by Amy Dougherty, FNP-BC, AGAC 

Content on the DrHouse website is written by our medical content team and reviewed by qualified MDs, PhDs, NPs, and PharmDs. We follow strict content creation guidelines to ensure accurate medical information. However, this content is for informational purposes only and not a substitute for professional medical advice, diagnosis, or treatment. For more information read our medical disclaimer.

Always consult with your physician or other qualified health providers about medical concerns. Never disregard professional medical advice or delay seeking it based on what you read on this website.

If you are experiencing high fever (>103F/39.4C), shortness of breath, difficulty breathing, chest pain, heart palpitations, abnormal bruising, abnormal bleeding, extreme fatigue, dizziness, new weakness or paralysis, difficulty with speech, confusion, extreme pain in any body part, or inability to remain hydrated or keep down fluids or feel you may have any other life-threatening condition, please go to the emergency department or call 911 immediately.

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Frequently asked questions

  • Yes, you can get a new prescription or refill an existing one online through DrHouse. You just need to start a consultation with one of our licensed providers and they will be able to assess your needs and provide you with a prescription if necessary.

    Please note that the final decision always rests with the doctor based on their professional judgment and your health needs.

  • There are certain medications that cannot be prescribed online by DrHouse physicians due to safety reasons. These include controlled substances, such as opioids and other narcotics, as well as drugs with a high potential for abuse or dependence. DrHouse physicians also don’t prescribe Gabapentin, medical marijuana, muscle relaxants, and HRT medications.

  • With DrHouse getting a new prescription or a refill for your current Rx is a straightforward and quick process. All you need to do is follow a few easy steps:

    • Download the DrHouse telehealth app on your mobile device.
    • Create an account by providing basic information and medical history.
    • Start an on-demand virtual video consultation with one of our licensed physicians.
    • Discuss your medical needs and concerns with one of our physicians.
    • A doctor will review your medical history, symptoms, and current medications (if any) to determine if an online prescription is appropriate for you.
    • If a physician approves, they will electronically send a new prescription or refill request to the pharmacy of your choice.
    • Pick up your medication from the pharmacy.

    DrHouse makes it easy for you to get an online prescription from the comfort of your own home. No more waiting in line at the doctor’s office or pharmacy, and no need to take time off work to see a doctor. Our telehealth platform allows you to access quality medical care from anywhere with an internet connection.

    For more information about how our telehealth platform works visit our “How DrHouse Works” page.

  • During your virtual consultation with a DrHouse physician, you will have the opportunity to discuss your medical needs and concerns.

    The consultation will consist of a video call where a physician will assess your medical history and ask you questions about your symptoms and any other relevant information. This is to ensure that a physician has all the necessary information to make an informed decision about your prescription.

    You can also ask any questions or clarify any doubts you may have about your condition or medication. Our physicians are happy to address any concerns you may have.

    Once a physician has assessed your needs, they will determine if and what type of prescription is appropriate for you. If a new prescription or refill is approved, a doctor will send it electronically to your chosen pharmacy.

  • With our on-demand telehealth service, you have the opportunity to see the first available doctor in as little as 10 to 15 minutes. However, the exact consult time will depend on the complexity of your case and the thoroughness required by the healthcare provider to make an informed decision.

  • Absolutely, it is safe to get an online prescription from DrHouse. We are committed to ensuring the highest standards of patient safety and privacy.

    All our providers are highly qualified US-based physicians and often affiliated with major hospitals. They are board-certified and from the top U.S. medical schools with an average of 20 years of experience.

    We strictly adhere to HIPAA regulations, ensuring your personal and medical information is kept secure and confidential. Also, we comply with all applicable state and federal laws related to telehealth and the prescribing of medications.

    Therefore, you can rest assured knowing that your safety and privacy are our top priorities when you use DrHouse’s services.

  • DrHouse strives to provide accessible and affordable telehealth services. DrHouse urgent care, primary care, and specialist visits are $129 or your copay. This includes everything from your initial consultation through to the prescription of your medication.

    The cost of a doctor’s visit may be covered fully by your insurance. A typical copay is around $25. We recommend checking with your insurance provider to understand the extent of your coverage for telehealth services.

    To learn more about how much DrHouse costs, visit our pricing page

  • Yes, DrHouse accepts most major insurances, including Blue Cross Blue Shield, Aetna, and Medicare. The extent of coverage may vary depending on your individual plan.

  • Our physicians are able to prescribe up to a 90-day prescription without labs for any previously prescribed medication if it’s medically appropriate and is not classified as a controlled substance.

    DrHouse physicians also don’t prescribe Gabapentin, medical marijuana, muscle relaxants, and HRT medications.

    DrHouse physicians use their medical judgment to determine whether to prescribe and the duration.

    In certain cases, the prescription may be limited to 30 days or less. There also may be a 12-month cap for some prescriptions without labs. For medications requiring annual monitoring (such as blood work or imaging), the maximum prescription limit is 90 days within a year without labs.

    DrHouse physicians can refer patients to labs for longer prescription periods or refills.