Monodox (Doxycycline): Uses, Side Effects, And Dosage

Written by: Jessica Guht Medically reviewed by: Amy Dougherty, FNP-BC, AGAC
Jessica Guht
Categorized as Antibiotics
Created on:
Jessica Guht
Categorized as Antibiotics

There are many antibiotics, with each type used to treat their own specific infections. However, some antibiotics are able to treat a range of infections, and that includes Monodox.

Monodox (Doxycycline) is an antibiotic used to treat infections such as UTIs, STIs, acne, and bacteria-based respiratory infections. It is a highly effective antibiotic, but it is vital to follow a doctor’s prescription orders to ensure that it kills all the bacteria.

Table of Contents

What Is Monodox?

Monodox is a name brand for doxycycline, an antibiotic used to treat various bacterial infections found throughout the body. It accomplishes this by preventing the growth of bacteria. Monodox interferes with the bacteria’s protein synthesis, and without these proteins, the bacteria cannot function.

So, while Monodox does not kill the bacteria, it prevents their reproduction.

What Is Monodox Used For?

It is important to note that, as an antibiotic, Monodox is not effective against viral infections such as the cold or flu.

However, Monodox is used to treat a range of bacterial infections, including:


When bacteria infect pores, they produce an oily substance that then causes acne. By killing the bacteria that infect pores, Monodox helps to treat acne.

Additionally, Monodox can also help to decrease inflammation causing rosacea, providing another way that it helps to improve skin appearance. However, Monodox does not treat facial redness caused by rosacea, it only treats any acne-like lesions that form. 

Respiratory Infections

Many respiratory infections due to bacteria, such as pneumonia, can be treated with Monodox.

Urinary Tract Infections (UTIs)

UTIs occur when bacteria enter the urethra and travel up the urinary tract to the bladder.

Depending on the bacteria found in the urine, Monodox may be used to treat the UTI.

Eye infections

Monodox is a common oral prescription for treating specific types of eye infections. It treats the infection by killing the bacteria while also providing strong anti-inflammatory effects.

Genital Infections

Many sexually transmitted infections (STIs) caused by bacteria, such as chlamydia or gonorrhea, can be treated by Monodox. However, STIs due to a viral infection cannot be treated with Monodox.

Intestinal Infections

Bacteria such as E. coli can cause severe gastrointestinal infections, but Monodox can help to treat these cases by preventing the bacteria from reproducing.

Infections Spread by Mites, Lice, Ticks, And Infected Animals

One of the infections included in this grouping is malaria, which is spread by infected mosquitoes. Monodox may be prescribed as a way to prevent malaria or used in combination with another medication to treat it.

Whatever the intent of the medication, it is essential to follow your doctor’s dosing instructions to give yourself optimal protection against malaria.

While doxycycline can help to prevent malaria, it is not complete protection against its transmission. Because of this, it is important to follow other preventative measures such as wearing long clothes, sleeping under a mosquito net, and using insect repellent.

Monodox Side Effects

Some of the side effects of Monodox can include:

  • nausea
  • vomiting
  • stomach pain
  • sore throat
  • diarrhea
  • anxiety
  • swollen tongue
  • dry mouth
  • back pain
  • loss of appetite

There are also some serious side effects of Monodox, which include:

  • chest pain
  • hives
  • joint pain
  • headache
  • skin peeling
  • blurred vision
  • skin redness
  • unusual bruising or bleeding
  • skin blistering
  • rash with fever

If you are experiencing any of these severe side effects, it is crucial to see a doctor immediately. Additionally, seek immediate medical attention if you are experiencing bloody or watery stools, stomach cramps, or fever while taking this antibiotic or during the two months afterward.

How to Take Monodox?

Monodox comes as an oral antibiotic that is taken by mouth. It is typically recommended to take it on an empty stomach, usually an hour before eating or two hours after. Some people may find that it upsets their stomach; if this is the case, you can take it with a little bit of food. Monodox also works best when taken at regular intervals, so try to take it at the same time(s) each day.

It is best to follow your doctor’s instructions for taking Monodox to minimize side effects and promote antibiotic effectiveness.

Additionally, it is important to take Monodox for the complete course prescribed, even if your symptoms improve, to ensure that the bacteria are completely killed off. By stopping Monodox too soon, the bacteria may keep growing, and your infection could return. It also increases the chances of developing antibiotic-resistant bacteria that do not respond to Monodox when the infection returns.

If your symptoms are not improving, or appear to be getting worse, be sure to let your doctor know.

While taking Monodox, it is typically recommended to avoid taking other antibiotics (unless your doctor prescribes otherwise). Additionally, Monodox can cause your skin to be more sensitive to the sun, so try to avoid direct sunlight and wear sunscreen and sunglasses if you do have to go outside.

Calcium supplements, iron supplements, antacids, and laxatives can prevent the body from absorbing doxycycline, so avoid taking them two hours before and after taking Monodox.

How Can DrHouse Help You?

If you are experiencing an infection, you can complete an entirely virtual consultation using DrHouse, which puts you in contact with an online doctor in just 15 minutes. Through this consultation, your doctor can consider your symptoms and prescribe you an antibiotic, such as Monodox, to help treat the infection.

For those planning to travel to a location at high risk of malaria transmission, meeting with an online doctor is a great way to receive preventative medication to help protect your health while you travel. 

Key Takeaways

Monodox is an antibiotic that treats bacterial infections by preventing bacteria from reproducing. It is used to treat a range of infections, including UTIs, acne, STIs, and pneumonia.

When taking Monodox, or any antibiotic, it is crucial to follow the instructions listed by your doctor. This helps to limit side effects and ensure that the medication is effective. Additionally, it is important to complete the entire course of antibiotics, even if symptoms improve. Failing to do so increases the risk of recurring infections and antibiotic-resistant bacteria.

If you are experiencing the symptoms of a bacterial infection, an online doctor can consider your symptoms to determine if Monodox is the ideal antibiotic for you.


Content on the DrHouse website is written by our medical content team and reviewed by qualified MDs, PhDs, NPs, and PharmDs. We follow strict content creation guidelines to ensure accurate medical information. However, this content is for informational purposes only and not a substitute for professional medical advice, diagnosis, or treatment. For more information click here.

Always consult with your physician or other qualified health providers about medical concerns. Never disregard professional medical advice or delay seeking it based on what you read on this website.

If you are experiencing high fever (>103F/39.4C), shortness of breath, difficulty breathing, chest pain, heart palpitations, abnormal bruising, abnormal bleeding, extreme fatigue, dizziness, new weakness or paralysis, difficulty with speech, confusion, extreme pain in any body part, or inability to remain hydrated or keep down fluids or feel you may have any other life-threatening condition, please go to the emergency department or call 911 immediately.

About DrHouse

DrHouse provides 24/7 virtual urgent care, men’s health, women’s health and online prescriptions.

  • On-demand virtual visits
  • 24/7 care support
  • Prescriptions as needed

DrHouse provides:

  • Online Doctor

  • Telehealth Services

  • Online Prescriptions

  • Antibiotics Online

  • Doxycycline Online

Recent Articles


Essential Oils for UTIs: Can They Help Treat a UTI?

Jessica Guht Dec. 04, 2023


Is Keflex (Cephalexin) a Broad-Spectrum Antibiotic?

Jessica Guht Nov. 27, 2023


Is Cipro (Ciprofloxacin) a Broad-Spectrum Antibiotic?

Jessica Guht Nov. 27, 2023


Is Doxycycline a Broad-Spectrum Antibiotic?

Jessica Guht Nov. 27, 2023


What Doctor to See for a UTI?

Jessica Guht Nov. 16, 2023



on your schedule

Skip the unnecessary waiting room,
see a board-certified clinician now.

Start an Online Visit
Available in 50 states. No insurance needed.

Prescriptions as needed
Renew or get a new Rx.

On-demand virtual visits
See a clinician in 15 minutes.

24/7 care support
We are here to help you.

  • 1

    Download the DrHouse app.
    Set up your free account in a minute.

  • 2

    Start a visit with an online doctor. Wait time is less than 15 minutes.

  • 3

    Get an Rx from your preferred pharmacy. Pick up a Rx nearby or get it delivered to you.

Download our app