Get a Zofran Prescription Online (Ondansetron)

Get a new prescription for Zofran (ondansetron) or refill your medication online.

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Available in 50 states. Insurance accepted.

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¹Having a visit does not guarantee a medication will be ordered or refilled. It is the doctors’ professional decision. It is prohibited by law to prescribe or refill controlled substances via virtual visits. ²Your provider may recommend follow-up care, including additional services that may not be included in the visit price.

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Zofran (Ondansetron)

Zofran is the brand name of Ondansetron, a medication commonly used to prevent the symptoms of nausea and vomiting. It is often prescribed to patients who are undergoing treatments for cancer such as chemotherapy, radiation therapy, or are undergoing surgery and are experiencing vomiting or nausea caused by the medication.

Approved for medical use in the 1990s, Zofran in the form of Ondansetron has had more than 11 million prescriptions in the United States in recent years and has been used in a number of other treatments, such as morning sickness, gastroenteritis, and other instances of vomiting. As a medicine, it can either be administered orally in the form of a pill or it can be directly injected into the muscle or a vein.

What Is Zofran Prescribed For?

Zofran is commonly prescribed by doctors for patients undergoing treatments that may result in nausea and vomiting due to the drugs being used. Initially used to control chemotherapy-induced nausea and vomiting and nausea and vomiting post-operation with great success, it has also been used in gastroenteritis, a common condition that causes diarrhea and vomiting induced by bacteria or a viral stomach bug.

It has also been used with pregnant women when other anti-nausea drugs have failed, but Zofran has predominantly been used with patients who have undergone chemotherapy and operations as the body sees cancer medicines.

How Does Zofran Work?

Zofran is part of a class of medications called the serotonin 5-HT3 receptor antagonists and works by blocking the action of serotonin, which is a natural substance that may cause nausea and vomiting. When a foreign body is detected, this flips the switch in the brain known as the “vomiting center.” Zofran or Ondansetron is commonly prescribed as an effective solution to this. When Zofran blocks the actions of chemicals in the body that trigger nausea and vomiting, the individual will not experience nausea or vomiting associated with either their cancer treatments or unique ailment.

What Are the Side Effects of Zofran?

Common side effects of taking Zofran include the following:

  • Lightheadedness
  • Dizziness
  • Headaches
  • Tiredness, fatigue, or drowsiness
  • Constipation, stomach pains, or bloating
  • Jaundice (the yellowing of the skin or eyes)
  • Temporary vision loss or blurred vision, which could last from a few minutes to a number of hours

Although uncommon, Zofran can also increase the levels of serotonin in the body, which may cause a condition called serotonin syndrome/toxicity, which is classed as extreme nerve cell activities. If an individual experiences this, it may cause a number of symptoms including hallucinations, fever, overactive reflexes, vomiting, diarrhea, loss of coordination, a fast heart rate, and fainting. It is extremely life-threatening and should be dealt with urgently.

Frequently Asked Questions About Zofran (Ondansetron)

How to Take Zofran?

Zofran should be taken exactly as prescribed and the medicine should not be taken in larger or smaller amounts or for longer than the recommended dose.

Zofran is usually prescribed in pill form and should be placed in the mouth and be allowed to dissolve without chewing or swallowing. If Zofran is prescribed in liquid form, the medicine should be measured with the dosing syringe or the special dose-measuring spoon or medicine cup and administered orally. It should be taken either 30 minutes or 1 to 2 hours before chemotherapy treatment depending on the nature of the treatment, and can be taken with or without food and up to 3 times a day for 1 to 2 days after the chemotherapy or radiation treatment is finished.

What to Avoid While Taking Zofran?

When taking Zofran there are drugs that have been known to interfere with it, including:

  • Apomorphine (Apokyn), commonly used to treat Parkinson’s Disease and is also used to stimulate vomiting.
  • Types of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) and serotonin and noradrenaline reuptake inhibitors (SNRIs), which affect the serotonin levels in the brain.
  • Medicines containing Phenytoin, Carbamazepine, and Rifampicin, which increase the liver enzyme CYP3A4, which can cause Apomorphine to be expelled from the body quicker, therefore decreasing the effects of the medication.

Can You Get Zofran (Ondansetron) Over the Counter?

No, Zofran is not available over the counter without a prescription from a licensed healthcare provider.

 

For more detailed information about Zofran (ondansetron), you can refer to the following sources:

Frequently asked questions