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How much does a visit to get a Zofran prescription cost?

Physician Visit
One-time visit with a physician for diagnosis, treatment, Rx, labs, referrals, and doctor’s notes.
Copay or $129 without insurance.
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See the first available physician, or schedule a visit with a physician you like.
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You can request a refund after your visit if we are unable to provide care.
Having a visit does not guarantee a medication will be ordered or refilled. It is clinicians’ professional decision. It is prohibited by law to prescribe or refill controlled substances via virtual visits. Your provider may recommend follow-up care, including additional services that may not be included in visit price.

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Zofran (Ondansetron)

Zofran is the brand name of Ondansetron, a medication commonly used to prevent the symptoms of nausea and vomiting. It is often prescribed to patients who are undergoing treatments for cancer such as chemotherapy, radiation therapy, or are undergoing surgery and are experiencing vomiting or nausea caused by the medication.

Approved for medical use in the 1990s, Zofran in the form of Ondansetron has had more than 11 million prescriptions in the United States in recent years and has been used in a number of other treatments, such as morning sickness, gastroenteritis, and other instances of vomiting. As a medicine, it can either be administered orally in the form of a pill or it can be directly injected into the muscle or a vein.

What Is Zofran Prescribed For?

Zofran is commonly prescribed by doctors for patients undergoing treatments that may result in nausea and vomiting due to the drugs being used. Initially used to control chemotherapy-induced nausea and vomiting and nausea and vomiting post-operation with great success, it has also been used in gastroenteritis, a common condition that causes diarrhea and vomiting induced by bacteria or a viral stomach bug.

It has also been used with pregnant women when other anti-nausea drugs have failed, but Zofran has predominantly been used with patients who have undergone chemotherapy and operations as the body sees cancer medicines.

How Does Zofran Work?

Zofran is part of a class of medications called the serotonin 5-HT3 receptor antagonists and works by blocking the action of serotonin, which is a natural substance that may cause nausea and vomiting. When a foreign body is detected, this flips the switch in the brain known as the “vomiting center.” Zofran or Ondansetron is commonly prescribed as an effective solution to this. When Zofran blocks the actions of chemicals in the body that trigger nausea and vomiting, the individual will not experience nausea or vomiting associated with either their cancer treatments or unique ailment.

What Are the Side Effects of Zofran?

Common side effects of taking Zofran include the following:

  • Lightheadedness
  • Dizziness
  • Headaches
  • Tiredness, fatigue, or drowsiness
  • Constipation, stomach pains, or bloating
  • Jaundice (the yellowing of the skin or eyes)
  • Temporary vision loss or blurred vision, which could last from a few minutes to a number of hours

Although uncommon, Zofran can also increase the levels of serotonin in the body, which may cause a condition called serotonin syndrome/toxicity, which is classed as extreme nerve cell activities. If an individual experiences this, it may cause a number of symptoms including hallucinations, fever, overactive reflexes, vomiting, diarrhea, loss of coordination, a fast heart rate, and fainting. It is extremely life-threatening and should be dealt with urgently.

Frequently Asked Questions About Zofran (Ondansetron)

How to Take Zofran?

Zofran should be taken exactly as prescribed and the medicine should not be taken in larger or smaller amounts or for longer than the recommended dose.

Zofran is usually prescribed in pill form and should be placed in the mouth and be allowed to dissolve without chewing or swallowing. If Zofran is prescribed in liquid form, the medicine should be measured with the dosing syringe or the special dose-measuring spoon or medicine cup and administered orally. It should be taken either 30 minutes or 1 to 2 hours before chemotherapy treatment depending on the nature of the treatment, and can be taken with or without food and up to 3 times a day for 1 to 2 days after the chemotherapy or radiation treatment is finished.

What to Avoid While Taking Zofran?

When taking Zofran there are drugs that have been known to interfere with it, including:

  • Apomorphine (Apokyn), commonly used to treat Parkinson’s Disease and is also used to stimulate vomiting. 
  • Types of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) and serotonin and noradrenaline reuptake inhibitors (SNRIs), which affect the serotonin levels in the brain. 
  • Medicines containing Phenytoin, Carbamazepine, and Rifampicin, which increase the liver enzyme CYP3A4, which can cause Apomorphine to be expelled from the body quicker, therefore decreasing the effects of the medication.

Can You Get Zofran (Ondansetron) Over the Counter?

No, Zofran is not available over the counter without a prescription from a licensed healthcare provider.


For more detailed information about Zofran (ondansetron), you can refer to the following sources:

Content on the DrHouse website is written by our medical content team and reviewed by qualified MDs, PhDs, NPs, and PharmDs. We follow strict content creation guidelines to ensure accurate medical information. However, this content is for informational purposes only and not a substitute for professional medical advice, diagnosis, or treatment. For more information read our medical disclaimer.

Always consult with your physician or other qualified health providers about medical concerns. Never disregard professional medical advice or delay seeking it based on what you read on this website.

If you are experiencing high fever (>103F/39.4C), shortness of breath, difficulty breathing, chest pain, heart palpitations, abnormal bruising, abnormal bleeding, extreme fatigue, dizziness, new weakness or paralysis, difficulty with speech, confusion, extreme pain in any body part, or inability to remain hydrated or keep down fluids or feel you may have any other life-threatening condition, please go to the emergency department or call 911 immediately.

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Frequently asked questions

  • Yes, you can get a new prescription or refill an existing one online through DrHouse. You just need to start a consultation with one of our licensed providers and they will be able to assess your needs and provide you with a prescription if necessary.

    Please note that the final decision always rests with the doctor based on their professional judgment and your health needs.

  • There are certain medications that cannot be prescribed online by DrHouse physicians due to safety reasons. These include controlled substances, such as opioids and other narcotics, as well as drugs with a high potential for abuse or dependence. DrHouse physicians also don’t prescribe Gabapentin, medical marijuana, muscle relaxants, and HRT medications.

  • With DrHouse getting a new prescription or a refill for your current Rx is a straightforward and quick process. All you need to do is follow a few easy steps:

    • Download the DrHouse telehealth app on your mobile device.
    • Create an account by providing basic information and medical history.
    • Start an on-demand virtual video consultation with one of our licensed physicians.
    • Discuss your medical needs and concerns with one of our physicians.
    • A doctor will review your medical history, symptoms, and current medications (if any) to determine if an online prescription is appropriate for you.
    • If a physician approves, they will electronically send a new prescription or refill request to the pharmacy of your choice.
    • Pick up your medication from the pharmacy.

    DrHouse makes it easy for you to get an online prescription from the comfort of your own home. No more waiting in line at the doctor’s office or pharmacy, and no need to take time off work to see a doctor. Our telehealth platform allows you to access quality medical care from anywhere with an internet connection.

    For more information about how our telehealth platform works visit our “How DrHouse Works” page.

  • During your virtual consultation with a DrHouse physician, you will have the opportunity to discuss your medical needs and concerns.

    The consultation will consist of a video call where a physician will assess your medical history and ask you questions about your symptoms and any other relevant information. This is to ensure that a physician has all the necessary information to make an informed decision about your prescription.

    You can also ask any questions or clarify any doubts you may have about your condition or medication. Our physicians are happy to address any concerns you may have.

    Once a physician has assessed your needs, they will determine if and what type of prescription is appropriate for you. If a new prescription or refill is approved, a doctor will send it electronically to your chosen pharmacy.

  • With our on-demand telehealth service, you have the opportunity to see the first available doctor in as little as 10 to 15 minutes. However, the exact consult time will depend on the complexity of your case and the thoroughness required by the healthcare provider to make an informed decision.

  • Absolutely, it is safe to get an online prescription from DrHouse. We are committed to ensuring the highest standards of patient safety and privacy.

    All our providers are highly qualified US-based physicians and often affiliated with major hospitals. They are board-certified and from the top U.S. medical schools with an average of 20 years of experience.

    We strictly adhere to HIPAA regulations, ensuring your personal and medical information is kept secure and confidential. Also, we comply with all applicable state and federal laws related to telehealth and the prescribing of medications.

    Therefore, you can rest assured knowing that your safety and privacy are our top priorities when you use DrHouse’s services.

  • DrHouse strives to provide accessible and affordable telehealth services. DrHouse urgent care, primary care, and specialist visits are $129 or your copay. This includes everything from your initial consultation through to the prescription of your medication.

    The cost of a doctor’s visit may be covered fully by your insurance. A typical copay is around $25. We recommend checking with your insurance provider to understand the extent of your coverage for telehealth services.

    To learn more about how much DrHouse costs, visit our pricing page

  • Yes, DrHouse accepts most major insurances, including Blue Cross Blue Shield, Aetna, and Medicare. The extent of coverage may vary depending on your individual plan.

  • Our physicians are able to prescribe up to a 90-day prescription without labs for any previously prescribed medication if it’s medically appropriate and is not classified as a controlled substance.

    DrHouse physicians also don’t prescribe Gabapentin, medical marijuana, muscle relaxants, and HRT medications.

    DrHouse physicians use their medical judgment to determine whether to prescribe and the duration.

    In certain cases, the prescription may be limited to 30 days or less. There also may be a 12-month cap for some prescriptions without labs. For medications requiring annual monitoring (such as blood work or imaging), the maximum prescription limit is 90 days within a year without labs.

    DrHouse physicians can refer patients to labs for longer prescription periods or refills.