Get a Cymbalta
Prescription Online

Get a new Cymbalta prescription or refill your medication online.

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Available in 50 states. No insurance needed.

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How to get a Cymbalta prescription online?

Download the DrHouse app. Set up your free account in a minute.


Start a visit with an online doctor. Wait time is less than 15 minutes.


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How much does a visit to get a Cymbalta prescription cost?

Physician Visit
One-time visit with a physician for diagnosis, treatment, Rx, labs, referrals, and doctor’s notes.
Copay or $129 without insurance.
24/7 virtual visits
See the first available physician, or schedule a visit with a physician you like.
Live customer support
Chat with our customer support whenever necessary. They are here for you 24/7.
Get a real doctor’s note
Get a doctor’s excuse and/or clearance for your school or work if needed.
100% treatment guarantee
You can request a refund after your visit if we are unable to provide care.
Having a visit does not guarantee a medication will be ordered or refilled. It is clinicians’ professional decision. It is prohibited by law to prescribe or refill controlled substances via virtual visits. Your provider may recommend follow-up care, including additional services that may not be included in visit price.

See why people turn to DrHouse...


Cymbalta (Duloxetine)

Cymbalta, also known as duloxetine hydrochloride, is a type of antidepressant known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It comes in the form of a pill or capsule that is swallowed whole. Cymbalta has the potential to help improve a variety of symptoms associated with depression, such as an individual’s disposition, appetite, sleep, and energy levels.

The reuptake of the neurotransmitters serotonin and norepinephrine in the central nervous system can be inhibited by duloxetine because it is an SNRI. This increases the amount of these neurotransmitters that are available in the brain. Because of these brain chemicals’ role in helping to regulate mood, elevating their levels can be an effective treatment for depression.

What is Cymbalta Prescribed For?

Cymbalta is prescribed to patients suffering from major depressive disorder as a treatment option. In clinical trials, the efficacy of Cymbalta for longer-term use, which is defined as use lasting more than nine weeks, has not been systematically evaluated. In addition, it is utilized in the treatment of diabetic peripheral neuropathic pain, generalized anxiety disorder, fibromyalgia, and chronic musculoskeletal pain.

Off-label uses of Cymbalta include the treatment of stress urinary incontinence, chronic fatigue syndrome, and lower back pain.

How Does Cymbalta Work?

The reuptake of serotonin and norepinephrine in the central nervous system can be blocked by the medication Cymbalta. It does this by acting on dopamine reuptake pumps, which results in an increase in the amount of dopamine that is able to diffuse throughout the brain. In addition to this, it raises levels of anti-inflammatory cytokines and lowers levels of pro-inflammatory cytokines, both of which contribute to the alleviation of depressive symptoms. It is believed that the blocking of sodium channels is the mechanism responsible for the analgesic effects of this medication.

What Are the Side Effects of Cymbalta?

Symptoms such as a headache, nausea, diarrhea, dry mouth, decreased appetite, increased perspiration, feeling nervous, restless, fatigued, sleepy, or unable to sleep may be caused by Cymbalta. As long as you keep taking the medication as prescribed, you should notice an improvement in these symptoms within the first week or two.

Sexual side effects, such as difficulties with orgasm or ejaculatory delay, as well as increases in blood pressure, frequently do not improve with continued use of the medication.

Duloxetine has been linked to extremely rare cases of liver failure, which has on occasion, been fatal. Those who have heavy alcohol use or chronic liver disease are at a greater risk for developing this condition.

Patients who took duloxetine sometimes experienced orthostatic hypotension, which refers to a drop in blood pressure when the patient stood up or got out of bed after sleeping. Patients who are also taking medication to treat their high blood pressure may be at an increased risk.

Antidepressants known as SNRIs, such as duloxetine, have been linked to an increased risk of bleeding events.  This may include gums that bleed more easily, nosebleeds, or bleeding from the digestive tract or gastrointestinal tract.

Frequently Asked Questions About Cymbalta (Duloxetine)

How to Use Cymbalta?

You should take this medication orally as directed by your physician, which is typically once or twice daily, regardless of whether you take it with or without food. If you are experiencing nausea, taking this medication with food may be of assistance. Take the capsule as directed and completely. You should not chew the capsule, crush it, or mix its contents with food or liquid in any way. This can cause the drug to be released all at once, which raises the risk of experiencing adverse effects.

What to Avoid While Using Cymbalta?

While you are taking antidepressant medication, it is important that you abstain from drinking alcohol and using illegal drugs. They have the potential to lessen the positive effects of the medication (such as making your condition worse) and increase the negative effects (such as sedation). Consuming alcohol while taking duloxetine raises the likelihood of developing liver problems.

Can You Get Cymbalta Over-The-Counter (OTC)?

No, Cymbalta (duloxetine) is not available over-the-counter and can only be obtained with a prescription from a licensed physician.

Can You Get a Duloxetine Prescription Online?

Yes, you can receive an online prescription for Duloxetine (Cymbalta) through DrHouse after a virtual consultation with our licensed physicians. They will review your medical history and current condition to determine if Duloxetine is the best course of treatment for you.


For more detailed information about Cymbalta (Duloxetine), you can refer to the following sources:


The content on this page has been medically reviewed for accuracy and comprehensiveness by Amy Dougherty, FNP-BC, AGAC 

Content on the DrHouse website is written by our medical content team and reviewed by qualified MDs, PhDs, NPs, and PharmDs. We follow strict content creation guidelines to ensure accurate medical information. However, this content is for informational purposes only and not a substitute for professional medical advice, diagnosis, or treatment. For more information read our medical disclaimer.

Always consult with your physician or other qualified health providers about medical concerns. Never disregard professional medical advice or delay seeking it based on what you read on this website.

If you are experiencing high fever (>103F/39.4C), shortness of breath, difficulty breathing, chest pain, heart palpitations, abnormal bruising, abnormal bleeding, extreme fatigue, dizziness, new weakness or paralysis, difficulty with speech, confusion, extreme pain in any body part, or inability to remain hydrated or keep down fluids or feel you may have any other life-threatening condition, please go to the emergency department or call 911 immediately.

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Frequently asked questions

  • Yes, you can get a new prescription or refill an existing one online through DrHouse. You just need to start a consultation with one of our licensed providers and they will be able to assess your needs and provide you with a prescription if necessary.

    Please note that the final decision always rests with the doctor based on their professional judgment and your health needs.

  • There are certain medications that cannot be prescribed online by DrHouse physicians due to safety reasons. These include controlled substances, such as opioids and other narcotics, as well as drugs with a high potential for abuse or dependence. DrHouse physicians also don’t prescribe Gabapentin, medical marijuana, muscle relaxants, and HRT medications.

  • With DrHouse getting a new prescription or a refill for your current Rx is a straightforward and quick process. All you need to do is follow a few easy steps:

    • Download the DrHouse telehealth app on your mobile device.
    • Create an account by providing basic information and medical history.
    • Start an on-demand virtual video consultation with one of our licensed physicians.
    • Discuss your medical needs and concerns with one of our physicians.
    • A doctor will review your medical history, symptoms, and current medications (if any) to determine if an online prescription is appropriate for you.
    • If a physician approves, they will electronically send a new prescription or refill request to the pharmacy of your choice.
    • Pick up your medication from the pharmacy.

    DrHouse makes it easy for you to get an online prescription from the comfort of your own home. No more waiting in line at the doctor’s office or pharmacy, and no need to take time off work to see a doctor. Our telehealth platform allows you to access quality medical care from anywhere with an internet connection.

    For more information about how our telehealth platform works visit our “How DrHouse Works” page.

  • During your virtual consultation with a DrHouse physician, you will have the opportunity to discuss your medical needs and concerns.

    The consultation will consist of a video call where a physician will assess your medical history and ask you questions about your symptoms and any other relevant information. This is to ensure that a physician has all the necessary information to make an informed decision about your prescription.

    You can also ask any questions or clarify any doubts you may have about your condition or medication. Our physicians are happy to address any concerns you may have.

    Once a physician has assessed your needs, they will determine if and what type of prescription is appropriate for you. If a new prescription or refill is approved, a doctor will send it electronically to your chosen pharmacy.

  • With our on-demand telehealth service, you have the opportunity to see the first available doctor in as little as 10 to 15 minutes. However, the exact consult time will depend on the complexity of your case and the thoroughness required by the healthcare provider to make an informed decision.

  • Absolutely, it is safe to get an online prescription from DrHouse. We are committed to ensuring the highest standards of patient safety and privacy.

    All our providers are highly qualified US-based physicians and often affiliated with major hospitals. They are board-certified and from the top U.S. medical schools with an average of 20 years of experience.

    We strictly adhere to HIPAA regulations, ensuring your personal and medical information is kept secure and confidential. Also, we comply with all applicable state and federal laws related to telehealth and the prescribing of medications.

    Therefore, you can rest assured knowing that your safety and privacy are our top priorities when you use DrHouse’s services.

  • DrHouse strives to provide accessible and affordable telehealth services. DrHouse urgent care, primary care, and specialist visits are $129 or your copay. This includes everything from your initial consultation through to the prescription of your medication.

    The cost of a doctor’s visit may be covered fully by your insurance. A typical copay is around $25. We recommend checking with your insurance provider to understand the extent of your coverage for telehealth services.

    To learn more about how much DrHouse costs, visit our pricing page

  • Yes, DrHouse accepts most major insurances, including Blue Cross Blue Shield, Aetna, and Medicare. The extent of coverage may vary depending on your individual plan.

  • Our physicians are able to prescribe up to a 90-day prescription without labs for any previously prescribed medication if it’s medically appropriate and is not classified as a controlled substance.

    DrHouse physicians also don’t prescribe Gabapentin, medical marijuana, muscle relaxants, and HRT medications.

    DrHouse physicians use their medical judgment to determine whether to prescribe and the duration.

    In certain cases, the prescription may be limited to 30 days or less. There also may be a 12-month cap for some prescriptions without labs. For medications requiring annual monitoring (such as blood work or imaging), the maximum prescription limit is 90 days within a year without labs.

    DrHouse physicians can refer patients to labs for longer prescription periods or refills.